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Working at the NKI Netherlands Cancer Institute. Publications. Sun C, Wang L, Huang S, Heynen G, Prahallad A, Robert C, Haanen J. Blank C, Wesseling J, Willems S, Zecchin D, Hober S, Bapje P. Lieftink C, Mateus C, Vagner S, Grernrum W, Hofland I, Schlicker A. Wessels L, Beijersbergen R, Bardelli A, Nicolantonio F, Eggermont. A, Bernards R. 2. Reversible and adaptive resistance to BRAF. V6. 00. E inhibition in melanoma. Nature. 5. 087. Sun C, Hober S, Bertotti A, Zecchin D, Huang S, Galimi F. Cottino F, Prahallad A, Grernrum W, Tzani A, Schlicker A, Wessels. LF, Smit EF, Thunnissen E, Halonen P, Lieftink C, Beijersbergen RL. All CRACKs and SERIALs on ONE Site crack. To receive news and publication updates for BioMed Research International, enter your email address in the box below. The Netherlands Cancer Institute, for more than 100 years at the international forefront of cancer research and treatment. A modified and tailored human follicle isolation procedure improves follicle recovery and survival. Graphpad Prism Serial Number' title='Graphpad Prism Serial Number' />This chapter of the Protocols and Applications Guide describes the various cell viability assays and helps you choose the right method for your needs. Di Nicolantonio F, Bardelli A, Trusolino L, Bernards R 2. Intrinsic resistance to MEK inhibition in KRAS mutant lung and. ERBB3. Cell Rep. Apr 1. Bajpe PK, Heynen GJ, Mittempergher L, Grernrum W, de Rink IA. Nijkamp W, Beijersbergen RL, Bernards R, Huang S 2. The. corepressor CTBP2 is a coactivator of retinoic acid receptor. X receptor in retinoic acid signaling. Mol Cell Biol. Aug 3. Huang S, Hlzel M, Knijnenburg T, Schlicker A, Roepman P. Mc. Dermott U, Garnett M, Grernrum W, Sun C, Prahallad A, Groenendijk. FH, Mittempergher L, Nijkamp W, Neefjes J, Salazar R, Ten Dijke P. Uramoto H, Tanaka F, Beijersbergen RL, Wessels LF, Bernards R. MED1. 2 controls the response to multiple cancer drugs through. TGF B receptor signaling. Cell. Nov. 2. 1 1. Prahallad A, Sun C, Huang S, Di Nicolantonio F, Salazar R. Zecchin D, Beijersbergen RL, Bardelli A, Bernards R. Unresponsiveness of colon cancer to BRAFV6. E inhibition through. EGFR. Nature. 2. 6 4. Kuiken HJ, Egan DA, Laman H, Bernards R, Beijersbergen RL, Dirac. AM. 2. 01. 2 Identification of F box only protein 7 as a negative. NF kappa. B signaling. J Cell Mol Med. 1. Westerman BA, Braat AK, Taub N, Potman M, Vissers JH, Blom M. Verhoeven E, Stoop H, Gillis A, Velds A, Nijkamp W, Beijersbergen. R, Huber LA, Looijenga LH, van Lohuizen M. A genome wide RNAi screen in mouse embryonic stem cells. Mp. 1 as a key mediator of differentiation. J. Exp Med. 1. 9 2. Nijwening JH, Geutjes EJ, Bernards R, Beijersbergen RL. The histone demethylase Jarid. Kdm. 5b is a novel. Rb pathway and associates with E2f target genes in. MEFs during senescence. PLo. S One. 69 e. Epub 2. 01. 1 Sep 2. Pub. Med PMID 2. Pub. Med Central PMCID PMC3. Paul P, van den Hoorn T, Jongsma ML, Bakker MJ, Hengeveld R. Janssen L, Cresswell P, Egan DA, van Ham M, Ten Brinke A, Ovaa H. Beijersbergen RL, Kuijl C, Neefjes J. A Genome wide. multidimensional RNAi screen reveals pathways controlling MHC class. II antigen presentation. Cell. 1. 5 1. 452 2. Nijwening JH, Kuiken HJ, Beijersbergen RL. Screening for. modulators of cisplatin sensitivity unbiased screens reveal common. Cell Cycle. 1 1. Evers B,　Schut E,　van der Burg E, Braumuller TM. Egan DA, Holstege. H,　Edser P,　Adams DJ,　Wade Martins R,　Bouwman P,　Jonkers J. A high throughput pharmaceutical screen identifies compounds with. BRCA2 deficient tumors. Clin Cancer Res. 1 1. Hlzel M, Huang S, Koster J, Ora I, Lakeman A, Caron H, Nijkamp. W, Xie J, Callens T, Asgharzadeh S, Seeger RC, Messiaen L, Versteeg. R, Bernards R. 2. NF1 is atumor suppressor in neuroblastoma that determines retinoic. Cell. 2. 3 1. 422 2. Mullenders J, Fabius AW, van Dongen MM, Kuiken HJ, Beijersbergen. RL, Bernards R. 2. Interleukin 1. R associated. Mol Cancer Res. Apr 84 5. Albers HM,　van Meeteren LA, Egan DA,　van Tilburg. EW,　Moolenaar WH,　Ovaa H. Discovery and optimization of. J Med Chem. 8 5. Albers HM,　Dong A, van Meeteren LA,　Egan. DA,　Sunkara M,　van Tilburg EW,　Schuurman K,　van Tellingen. O,　Morris AJ,　Smyth SS,　Moolenaar WH,　Ovaa H. Boronic. acid based inhibitor of autotaxin reveals rapid turnover of LPA in. Proc Natl Acad Sci U S A. Drost J, Mantovani F, Tocco F, Elkon R, Comel A, Holstege H. Kerkhoven R, Jonkers J, Voorhoeve PM, Agami R, Del Sal G. BRD7 is a candidate tumour suppressor gene required for p. Nat Cell Biol. Apr 1. Mullenders J, Bernards R. Loss of function genetic. Oncogene. 1. 7 2. Mullenders J, von der Saal W, van Dongen MM, Reiff U, van. Willigen R, Beijersbergen RL, Tiefenthaler G, Klein C, Bernards R. Candidate biomarkers of response to an experimental cancer. RNA interference genetic. Clin Cancer Res. Sep 1. Hadrup SR,　Toebes M,　Rodenko B,　Bakker AH. H,　Schumacher TN. High throughput T cell epitope discovery. MHC peptide exchange. Methods Mol. Biol. Mullenders J, Fabius AW, Madiredjo M, Bernards R, Beijersbergen. RL. 2. 00. 9A large scale sh. RNA barcode screen. ARNTL as putative. PLo. S. One. 2. 00. Otto T, Horn S, Brockmann M, Eilers U, Schttrumpf L, Popov N. Kenney AM, Schulte JH, Beijersbergen R, Christiansen H, Berwanger. B, Eilers M. 2. 00. Stabilizationof N Myc is a critical function of Aurora A in human. Cancer Cell. 6 1. Fotheringham S, Epping MT, Stimson L, Khan O, Wood V, Pezzella. F, Bernards R, La Thangue NB. Genome wide loss of function. HDAC. inhibitor induced apoptosis. Cancer Cell. 6 1. Eichhorn PJ, Gili M, Scaltriti M, Serra V, Guzman M, Nijkamp W. Beijersbergen RL, Valero V, Seoane J, Bernards R, Baselga J. Phosphatidylinositol 3 kinase hyperactivation results in. TORphosphatidylinositol 3 kinase inhibitor NVP BEZ2. Cancer. Res. 1. 5 6. Herold S, Hock A, Herkert B, Berns K, Mullenders J. Beijersbergen R, Bernards R, Eilers M. Miz. 1 and Hect. H9. Top. BP1. EMBO J. Huang Q,　Gumireddy K,　Schrier M,　le Sage C,　Nagel R,　Nair S. Egan DA, Li A,　Huang. G,　Klein Szanto AJ,　Gimotty PA,　Katsaros D,　Coukos G,Zhang L,　Pur. E,　Agami R. 2. 00. The micro. RNAs mi. R 3. 73 and mi. R 5. Nat Cell Biol. Feb 1. Kuijl C, Savage ND, Marsman M, Tuin AW, Janssen L, Egan DA. Ketema M, van den Nieuwendijk R, van den Eeden SJ, Geluk A, Poot A. Marel G, Beijersbergen RL, Overkleeft H, Ottenhoff TH. Crossfit Is The Best Program For Bodybuilding here. Neefjes J. 2. 00. Intracellular bacterial growth is controlled by a. PKBAKT1. Nature. Le Sage C, Nagel R,　Egan　DA,　Schrier M,　Mesman. E,　Mangiola A,　Anile C,　Maira G,　Mercatelli N,　Ciafr SA,　Farace. MG,　Agami R. 2. 00. Regulation of the p. Kip. 1 tumor suppressor by. R 2. 21 and mi. R 2. EMBO J. 8 2. 61. Berns K, Horlings HM, Hennessy BT, Madiredjo M, Hijmans EM. Beelen K, Linn SC, Gonzalez Angulo AM, Stemke Hale K, Hauptmann M. Beijersbergen RL, Mills GB, van de Vijver MJ, Bernards R. A. functional genetic approach identifies the PI3. K pathway as a major. Cancer Cell. Oct 1. Popov N, Wanzel M, Madiredjo M, Zhang D, Beijersbergen R. Bernards R, Moll R, Elledge SJ, Eilers M. The. ubiquitin specific protease USP2. MYC stability. Nat. Cell Biol. Jul 97 7. Bernards R, Brummelkamp TR, Beijersbergen RL. RNA. libraries and their use in cancer genetics. Nat Methods. Sep 39 7. Review. Brummelkamp TR, Fabius AW, Mullenders J, Madiredjo M, Velds A. Kerkhoven RM, Bernards R, Beijersbergen RL. An sh. RNA barcode. MDM2. inhibitors. Nat Chem Biol. Apr 24 2. Nicke B, Bastien J, Khanna SJ, Warne PH, Cowling V, Cook SJ. Peters G, Delpuech O, Schulze A, Berns K, Mullenders J. Beijersbergen RL, Bernards R, Ganesan TS, Downward J, Hancock DC. Involvement of MINK, a Ste. Ras. oncogene induced growth arrest in human ovarian surface epithelial. Mol Cell. 9 2. 05 6. Kolfschoten IG, van Leeuwen B, Berns K, Mullenders J. Beijersbergen RL, Bernards R, Voorhoeve PM, Agami R. A. genetic screen identifies PITX1 as a suppressor of RAS activity and. Cell. 1. 7 1. 216 8. Brummelkamp TR, Berns K, Hijmans EM, Mullenders J, Fabius A. Heimerikx M, Velds A, Kerkhoven RM, Madiredjo M, Bernards R. Beijersbergen RL. Functional identification of. RNA interference screens.